Research

"My scientific studies have afforded me great gratification; and I am convinced that it will not be long before the whole world acknowledges the results of my work."

-- Gregor Johann Mendel

My Publications

Original and Review Articles

Sundarraj, K., Raghunath, A., Panneerselvam, L., Perumal, E., (2020). Fisetin inhibits autophagy in HepG2 cells via PI3K/Akt/mTOR and AMPK pathway. Nutrition and Cancer Epub ahead of print. Impact Factor: 2.363.

Tharmalingam, B., Mathivanan, M., Mani, K.S., Kaminsky, W., Raghunath, A., Jothi, M., Perumal, E., Murugesapandian, B. (2020). Selective detection of pyrophosphate anion by zinc ensemble of C3-symmetric triaminoguanidine-pyrrole conjugate and its biosensing applications. Analytica Chimica Acta 1103:192-201. Impact Factor: 5.977.

Raghunath, A*., Nagarajan, R*., Perumal, E. (2020). ZFARED: a database of the antioxidant response element in zebrafish. Current Bioinformatics 15:415-419. Impact Factor: 2.068.

Sundarraj, K*., Raghunath, A*., Panneerselvam, L., Perumal, E. (2019). Fisetin, a phytopolyphenol, targets apoptotic and necroptotic cell death in HepG2 cells. Biofactors 46(1):118-135. Impact Factor: 4.734.

Panneerselvam, L*., Raghunath, A*., Ravi, M.S*., Vetrivel, A., Subramaniam, V., Sundarraj, K., Perumal, E. (2019). Ferulic acid attenuates arsenic-induced cardiotoxicity in rats. Biotechnology and Applied Biochemistry 67:186-195. Impact Factor: 1.638.

Panneerselvam, L*., Raghunath, A*., Sundarraj, K., Perumal, E. (2019). Acute fluoride exposure alters myocardial redox and inflammatory markers in rats. Molecular Biology Reports 46:6155-6164. Impact Factor: 1.402.

Balasubramanian, S., Raghunath, A*., Perumal, E. (2019). Role of epigenetics in zebrafish development. Gene 718:144049. Impact Factor: 2.984.

Mani, R., Balasubramanian, S., Raghunath, A*., Perumal, E. (2019). Chronic exposure to copper oxide nanoparticles causes muscle toxicity in adult zebrafish. Environmental Science and Pollution Research International doi: 10.1007/s11356-019-06095-w. [Epub ahead of print] Impact Factor: 3.056.

Raghunath, A*., Nagarajan, R*., Sundarraj, K., Palanisamy, K., Perumal, E. (2019). Identification of compounds that inhibit the binding of Keap1a/Keap1b Kelch DGR domain with Nrf2 ETGE/DLG motifs in zebrafish. Basic & Clinical Pharmacology & Toxicology 125:259-270. Impact Factor: 2.651.

Raghunath, A*., Sundarraj, K*., Arfuso, F., Sethi, G., Perumal, E. (2018). Dysregulation of Nrf2 in hepatocellular carcinoma: Role in cancer progression and chemoresistance. Cancers 10(12): E481. Impact Factor: 6.126.

Raghunath, A*., Nagarajan, R*., Sundarraj, K., Panneerselvam, L., Perumal, E. (2018). Genome-wide identification and analysis of Nrf2 binding sites - Antioxidant response elements in zebrafish. Toxicology and Applied Pharmacology 53(4):169-186. Impact Factor: 3.347.

Ameeramja, J.,Raghunath, A., Perumal, E. (2018). Tamarind seed coat extract restores fluoride-induced hematological and biochemical alterations in rats. Environmental Science and Pollution Research International 25(26):26157-26166. Impact Factor: 3.056.

Raghunath, A., Sundarraj, K., Nagarajan, R., Arfuso, F., Bian, J., Kumar, A.P., Sethi, G., Perumal, E. (2018). Antioxidant response elements: Discovery, classes, regulation and potential applications. Redox Biology 17:297-314. Impact Factor: 9.986.

Sundarraj, K*., Raghunath, A*., Sundarraj, K., Perumal, E. (2018). A review on the chemotherapeutic potential of fisetin: In vitro evidences. Biomedicine Pharmacotherapy 97:928-940. Impact Factor: 4.545.

Panneerselvam, L*., Raghunath, A*., Perumal, E. (2017). Differential expression of myocardial heat shock proteins in rats acutely exposed to fluoride. Cell Stress and Chaperones 22:743-750. Impact Factor: 2.892.

Raghunath, A., Perumal, E. (2017). Metal oxide nanoparticles as antimicrobial agents: a promise for the future. International Journal of Antimicrobial Agents 22:743-750. Impact Factor: 4.621.

Sundarraj, K*., Raghunath, A*., Panneerselvam, L., Perumal, E. (2017). Iron oxide nanoparticles modulate heat shock proteins and organ specific markers expression in mice male accessory organs. Toxicology and Applied Pharmacology 317:12-24. Impact Factor: 3.347.

Panneerselvam, L., Raghunath, A., Perumal, E. (2017). Acute fluoride poisoning alters myocardial cytoskeletal and AMPK signaling proteins in rats. International Journal of Cardiology 229:96-101. Impact Factor: 3.229.

Sundarraj, K., Manickam, V., Raghunath, A., Periyasamy, M., Viswanathan, M. P., Perumal, E. (2017). Repeated exposure to iron oxide nanoparticles causes testicular toxicity in mice. Environmental Toxicology 32:594-608. Impact Factor: 3.292.

Raghunath, A*., Jeyabaskar, D*., Sundarraj, K*., Panneerselvam, L., Perumal, E. (2016). In silico prediction of microRNAs on fluoride induced sperm toxicity in mice. Food and Chemical Toxicology 98(Pt A):34-49. Impact Factor: 4.679.

Ganesan, S*., Anaimalai Thirumurthi, N*., Raghunath, A*., Vijayakumar, S., Perumal, E. (2016). Acute and sub-lethal exposure to copper oxide nanoparticles causes oxidative stress and teratogenicity in zebrafish embryos. Journal of Applied Toxicology 36:554-567. Impact Factor: 2.997.

Raghunath, A., Perumal, E. (2015). Micro-RNAs and their roles in eye disorders. Ophthalmic Research 53:169-186. Impact Factor: 1.961.

Purushothaman, S., Raghunath, A., Dhakshinamoorthy, V., Panneerselvam, L., Perumal, E. (2014). Acute exposure to titanium dioxide (TiO₂) induces oxidative stress in zebrafish gill tissues. Toxicological and Environmental Chemistry 96(6):890-905. Impact Factor: 1.050.

Book Chapters

Balasubramanian, S., Raghunath, A., Perumal, E. (2020). Nanoengineered biomaterials for neurodegenerative disorders. In: Masoud Mozafari Nanoengineered Biomaterials for Advanced Drug Delivery, Woodhead Publishing Series in Biomaterials. Elsevier. pp. 713-734.

Velankanni, P., Balasubramanian, S., Raghunath, A., Arfuso, G, Sethi, G., Perumal, E. (2019). Curcumin as a potential therapeutic for Alzheimer’s disease: A multi-targeted approach. In: M. K. Swamy, J. K . Patra, G. R. Rudramurthy (eds.). Medicinal Plants: Chemistry, Pharmacology, and Therapeutic Applications, CRC Press, Taylor and Francis Group. pp. 79-102.

Panneerselvam, L*., Raghunath, A*., Sundarraj, K., Perumal, E. (2019). HO-1/HSP32 and cardiac stress signaling. In: A.A.A. Asea, P. Kaur (eds.). Heat Shock Proteins in Signaling Pathways Vol. 17, In Press. Springer International Publishing AG.

Raghunath, A*., Panneerselvam, L*., Sundarraj, K., Perumal, E. (2018). Heat shock proteins and endoplasmic reticulum stress. In: A.A.A. Asea, P. Kaur (eds.). Heat Shock Proteins and Stress Vol. 15, 39-78. Springer International Publishing AG.

Raghunath, A., Perumal, E. (2018). Analysis of lethalith and malformations during zebrafish (Danio rerio) development. In: Luis Felix (ed.). Teratogenicity Testing: Methods and Protocols, Methods in Molecular Biology Vol. 1997, 337-363. Humana Press, New York, NY.

Raghunath, A., Sundarraj, K., Kanagaraj, V.V., Perumal, E. (2018). Plant sources as potential therapeutics for Alzheimer's disease. In: Parimelazhagan Thangaraj (ed.). Medicinal Plants: Promising future for health and new drugs 162-192. CRC Press, Taylor and Francis Group.

Conference Proceedings

Subramaniam, A., Sundarraj, K., Raghunath, A., Perumal, E. (2007). Emodin (1, 3, 8-trihydroxy-6-methylanthraquinone), a natural anthraquinone derivative induces oxidative stress and apoptosis in hepatocellular carcinoma cells. International Conference on “Herbal and Natural Components as the Future of Pharmacology”, and 7th Annual Meet of the National Society of Ethnopharmacology. 2017: 344-354.

* Joint First Author